BioChem™️ 5% Benzoyl Peroxide

Benzoyl peroxide (BPO) is an antimicrobial and keratolytic agent commonly used to treat acne.
It works by:

• Killing acne-causing bacteria (Cutibacterium acnes, formerly P. acnes)

• Unclogging pores through mild exfoliation

• Reducing inflammation in active breakouts

It’s available in over-the-counter (OTC) and prescription strengths in gels, creams, lotions, and washes.

Benefits

1. Effective Against Acne

   • Works on both inflammatory (pimples, pustules) and non-inflammatory (blackheads, whiteheads) acne.

2. Prevents Antibiotic Resistance

   • Often combined with topical or oral antibiotics to reduce bacterial resistance.

3. Quick Onset of Action

   • Can show visible improvement in 2–4 weeks with consistent use.

4. Suitable for Face & Body

   • Used on acne-prone areas like chest, back, and shoulders.

Uses

• Typical concentrations:

  • OTC: 2.5%, 5%, 10% (2.5% often as effective with less irritation)

  • Prescription: higher strengths or combined with retinoids/antibiotics

• Application:

  • Once or twice daily after cleansing; start with lower frequency to reduce irritation.

• Forms:

  • Leave-on gels/creams or rinse-off cleansers.

FDA Cautions & Safety

• FDA Status:

  • Benzoyl peroxide is monographed as an OTC acne treatment under the FDA Acne Drug Products Monograph (21 CFR Part 333, Subpart D).

  • It is considered safe and effective when used as directed.

• Potential Side Effects:

  • Dryness, peeling, redness, and mild burning—especially when starting.

  • May bleach hair, towels, and clothing.

• Rare FDA Warning (2014):

  • Very rare but serious allergic reactions or severe irritation can occur. FDA advises patch testing before first full use.

• Cautions:

  • Avoid excessive sun exposure; use sunscreen.

  • Introduce gradually if combining with retinoids or strong acids to avoid over-irritation.